| Identification | Back Directory | [Name]
6-FLUOROQUINAZOLIN-4-ONE | [CAS]
16499-56-2 | [Synonyms]
6-Fluoroquinazolin-4-ol
6-FLUOROQUINAZOLIN-4-ONE
6-fluoroquinazolin-4(3H)-one
6-Fluoro-3H-quinazolin-4-one
6-fluoro-1H-quinazolin-4-one
6-Fluoro-4-hydroxyquinazoline
4(3H)-Quinazolinone, 6-fluoro-
6-Fluoroquinazolin-4(3H)-one, 95+% | [Molecular Formula]
C8H5FN2O | [MDL Number]
MFCD05664873 | [MOL File]
16499-56-2.mol | [Molecular Weight]
164.14 |
| Chemical Properties | Back Directory | [Melting point ]
250 °C | [Boiling point ]
318.3±44.0 °C(Predicted) | [density ]
1.44±0.1 g/cm3(Predicted) | [storage temp. ]
Sealed in dry,Room Temperature | [pka]
1.28±0.20(Predicted) | [Appearance]
Off-white to light yellow Solid |
| Hazard Information | Back Directory | [Synthesis]
General procedure for the synthesis of 6-fluoro-4-hydroxyquinazoline from 2-amino-5-fluorobenzoic acid and the compound (CAS: 77287-34-4): operate with reference to the reaction and post-processing of Example 5, substituting only the type of o-aminobenzoic acid derivative. The specific experimental results are detailed in Table 4. | [References]
[1] Patent: EP1997812, 2008, A1. Location in patent: Page/Page column 8
[2] European Journal of Medicinal Chemistry, 2012, vol. 50, p. 264 - 273
[3] Molecules, 2006, vol. 11, # 6, p. 383 - 392
[4] Bioorganic and Medicinal Chemistry, 2007, vol. 15, # 11, p. 3768 - 3774
[5] Chemistry and Biodiversity, 2018, vol. 15, # 6, |
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J & K SCIENTIFIC LTD.
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Shanghai Ennopharm Co., Ltd.
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Cochemical Ltd.
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