| Identification | Back Directory | [Name]
(4R)-1-[(5-Chloro-1H-1,2,4-triazol-1-yl)methyl]-4-(3,4,5-trifluorophenyl)-2-pyrrolidinone | [CAS]
1651179-19-9 | [Synonyms]
SDI-118
(4R)-1-[(5-Chloro-1H-1,2,4-triazol-1-yl)methyl]-4-(3,4,5-trifluorophenyl)-2-pyrrolidinone | [Molecular Formula]
C13H10ClF3N4O | [MOL File]
1651179-19-9.mol | [Molecular Weight]
330.69 |
| Chemical Properties | Back Directory | [Boiling point ]
504.2±60.0 °C(Predicted) | [density ]
1.63±0.1 g/cm3(Temp: 20 °C; Press: 760 Torr)(Predicted) | [form ]
Solid | [pka]
-0.07±0.50(Predicted) | [color ]
Off-white to light yellow |
| Hazard Information | Back Directory | [Uses]
SDI-118 is an orally active modulator for synaptic vesicle glycoprotein 2A (SV2A) with an IC50 of 13 nM[1]. | [References]
[1] Botermans W, et al., SDI-118, a novel procognitive SV2A modulator: First-in-human randomized controlled trial including PET/fMRI assessment of target engagement. Front Pharmacol. 2023 Jan 17;13:1066447. DOI:10.3389/fphar.2022.1066447 |
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ChemOrigin Pharm
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15026428026 19002516454 |
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www.chemorigin.com |
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