ChemicalBook--->CAS DataBase List--->165187-25-7

165187-25-7

165187-25-7 Structure

165187-25-7 Structure
IdentificationBack Directory
[Name]

3,5-Pyridinedicarboxylic acid, 4-(2-chloro-3-cyanophenyl)-1,4-dihydro-2,6-dimethyl-, 3-(2-methoxyethyl) 5-(1-methylethyl) ester
[CAS]

165187-25-7
[Synonyms]

MEM1003
MEM-1003
MEM 1003
BAY-Z4406
BAY-Z-4406
BAY Z-4406
(Rac)-MEM1003
(Rac)MEM 1003,(Rac) MEM 1003
3,5-Pyridinedicarboxylic acid, 4-(2-chloro-3-cyanophenyl)-1,4-dihydro-2,6-dimethyl-, 3-(2-methoxyethyl) 5-(1-methylethyl) ester
[Molecular Formula]

C22H25ClN2O5
[MDL Number]

MFCD00940513
[MOL File]

165187-25-7.mol
[Molecular Weight]

432.9
Chemical PropertiesBack Directory
[Boiling point ]

540.6±50.0 °C(Predicted)
[density ]

1.25±0.1 g/cm3(Predicted)
[storage temp. ]

Store at -20°C
[solubility ]

DMSO : 125 mg/mL (288.75 mM; ultrasonic and warming and heat to 80°C)
[form ]

Solid
[pka]

2.68±0.70(Predicted)
[color ]

Light yellow to yellow
Hazard InformationBack Directory
[Uses]

(Rac)-MEM 1003 is the racemate of MEM 1003. MEM 1003, a dihydropyridine compound, is a potent L-type Ca2+ channel antagonist and has the potential for Alzheimer’s disease research[1].
[References]

[1] Gregory M Rose, et al. Efficacy of MEM 1003, a novel calcium channel blocker, in delay and trace eyeblink conditioning in older rabbits. Neurobiol Aging. 2007 May;28(5):766-73. DOI:10.1016/j.neurobiolaging.2006.03.006
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