| Identification | Back Directory | [Name]
Spiro[3-cyclohexene-1,4'(3'H)-[1H-7,9a]methanocyclohepta[c]pyran]-1',2,9'(4'aH)-trione, 5',6',7',8'-tetrahydro-6-(hydroxymethyl)-5,5-dimethyl-8'-methylene-, (1S,4'aS,6R,7'R,9'aS)- (9CI) | [CAS]
165337-71-3 | [Synonyms]
Laxiflorin B
Spiro[3-cyclohexene-1,4'(3'H)-[1H-7,9a]methanocyclohepta[c]pyran]-1',2,9'(4'aH)-trione, 5',6',7',8'-tetrahydro-6-(hydroxymethyl)-5,5-dimethyl-8'-methylene-, (1S,4'aS,6R,7'R,9'aS)- (9CI) | [Molecular Formula]
C20H24O5 | [MOL File]
165337-71-3.mol | [Molecular Weight]
344.4 |
| Hazard Information | Back Directory | [Uses]
Laxiflorin B, a herbal compound, is a novel selective ERK1/2 inhibitor that has antitumor activity[1]. | [References]
[1] Cheng-Yao Chiang, et al. A novel selective ERK1/2 inhibitor, Laxiflorin B, targets EGFR mutation subtypes in non-small-cell lung cancer. Acta Pharmacol Sin. 2023 Oct 10. DOI:10.1038/s41401-023-01164-w |
|
|