| Identification | Back Directory | [Name]
2-IMINO-4-METHYLPIPERIDINE ACETATE | [CAS]
165383-72-2 | [Synonyms]
NOS-IN-1
QNJYWSIQJFUBOR-UHFFFAOYSA-N
2-IMINO-4-METHYLPIPERIDINE ACETATE
(2)-IMINO-4-METHYLPIPERIDINE ACETATE SALT
4-Methyl-3,4,5,6-tetrahydropyridin-2-aMine acetate
3,4,5,6-TETRAHYDRO-4-METHYL-2-PYRIDINAMINE, ACETATE | [Molecular Formula]
C8H16N2O2 | [MDL Number]
MFCD01320530 | [MOL File]
165383-72-2.mol | [Molecular Weight]
172.22 |
| Chemical Properties | Back Directory | [Melting point ]
181-182°C | [storage temp. ]
Store at -20°C | [solubility ]
DMF: >5 mg/ml; DMSO: >6.5 mg/ml; Ethanol: >23 mg/ml; PBS pH 7.2: >25 mg/ml | [form ]
A crystalline solid | [color ]
White to off-white |
| Hazard Information | Back Directory | [Description]
2-Imino-4-methylpiperidine is a potent, general NOS inhibitor. It exhibits IC50 values of 0.1, 1.1, and 0.2 μM for inhibition of human iNOS, eNOS, and nNOS, respectively, at an arginine concentration of 30 μM. | [Uses]
2-Imino-4-methylpiperidine is a potent, general NOS inhibitor. It exhibits IC50 values of 0.1, 1.1, and 0.2 μM for inhibition of human iNOS, eNOS, and nNOS, respectively, at an arginine concentration of 30 μM. | [Uses]
A potent inhibitor of human iNOS (hNOS II) | [in vivo]
Following oral administration, NOS-IN-1 (compound 3; 10 mg/kg) decreases serum nitrite/nitrate levels in an in vivo rat endotoxin assay[1]. | [storage]
Store at -20°C |
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