| Identification | Back Directory | [Name]
4(1H)-Pyrimidinone,5-fluoro-2-methoxy-,hydrazone(9CI) | [CAS]
166524-64-7 | [Synonyms]
Florasulam intermediate
2-methoxy-4-indolyl-5-fluoropyrimidine
5-Fluoro-4-hydrazino-2-methoxypyrimidine
5-Fluoro-4-hydrazinyl-2-MethoxypyriMidine
2-Methoxy-4-hydrazinyl-5-fluoropyriMidine)
(5-fluoro-2-methoxy-4-pyrimidinyl)hydrazine
(5-fluoro-2-methoxypyrimidin-4-yl)hydrazine
(5-fluoro-2-methoxy-pyrimidin-4-yl)hydrazine
Pyrimidine, 5-fluoro-4-hydrazinyl-2-methoxy-
4(1H)-PyriMidinone,5-fluoro-2-Methoxy-,hydrazone
4(1H)-Pyrimidinone,5-fluoro-2-methoxy-,hydrazone(9CI)
(E)-5-fluoro-4-hydrazono-2-Methoxy-1,4-dihydropyriMidine
4(1H)-Pyrimidinone,5-fluoro-2-methoxy-,hydrazone(9CI) ISO 9001：2015 REACH | [EINECS(EC#)]
605-444-4 | [Molecular Formula]
C5H7FN4O | [MDL Number]
MFCD09955584 | [MOL File]
166524-64-7.mol | [Molecular Weight]
158.13 |
| Chemical Properties | Back Directory | [Melting point ]
>155°C (dec.) | [Boiling point ]
217.0±50.0 °C(Predicted) | [density ]
1.52±0.1 g/cm3(Predicted) | [storage temp. ]
Keep in dark place,Inert atmosphere,Store in freezer, under -20°C | [solubility ]
DMSO (Slightly), Methanol (Slightly) | [form ]
Solid | [pka]
4.23±0.70(Predicted) | [color ]
Pale Beige to Pale Brown | [InChI]
InChI=1S/C5H7FN4O/c1-11-5-8-2-3(6)4(9-5)10-7/h2H,7H2,1H3,(H,8,9,10) | [InChIKey]
CWCLTMYHVXUXDW-UHFFFAOYSA-N | [SMILES]
C1(OC)=NC=C(F)C(NN)=N1 |
| Hazard Information | Back Directory | [Synthesis]
the preparation method of 5-Fluoro-4-hydrazinyl-2-methoxypyrimidine, it is for starting raw material with 2-methoxyl group-5 FU 5 fluorouracil, first under the existence of organic solvent and acid binding agent, carry out chlorination reaction with phosphorus oxychloride and obtain the chloro-5-FU of 2-methoxyl group-4-, then carry out hydrazinolysis with hydrazine hydrate and be obtained by reacting 2-methoxyl group-4-diazanyl-5-FU. |
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