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16662-47-8

16662-47-8 Structure

16662-47-8 Structure
IdentificationBack Directory
[Name]

METHOXYVERAPAMIL HYDROCHLORIDE
[CAS]

16662-47-8
[Synonyms]

C13764
dl-D 600
Lu 30-029
CoMpound D 600
Methoxyverapamil
D 600 (vasodilator)
(+/-)-Methoxyverapamil
(+/-)-MethoxyverapamilHydrochloride
(±)-Methoxyverapamil hydrochloride Solution, 100ppm
(±)-Methoxyverapamil hydrochloride Solution, 1000ppm
(+/-)-METHOXYVERAPAMIL HYDROCHLORIDE (D6 00) (GALLOPAMIL)
5-[(3,4-Dimethoxyphenethyl)methylamino]-2-isopropyl-2-(3,4,5-trimethoxyphenyl)valeronitrile
5-((3,4-diMethoxyphenethyl)(Methyl)aMino)-2-isopropyl-2-(3,4,5-triMethoxyphenyl)pentanenitrile
5-((3,4-diMethoxyphenethyl)(Methyl)aMino)-2-isopropyl-2-(3,4,5-triMethoxyphenyl)pentanenitrile HCl
5-[[2-(3,4-Dimethoxyphenyl)ethyl](methyl)amino]-2-isopropyl-2-(3,4,5-trimethoxyphenyl)pentanenitrile
α-[3-[[2-(3,4-Dimethoxyphenyl)ethyl]methylamino]propyl]-3,4,5-trimethoxy-α-isopropylbenzeneacetonitrile
α-[3-[N-[2-(3,4-Dimethoxyphenyl)ethyl]-N-methylamino]propyl]-3,4,5-trimethoxy-α-isopropylbenzeneacetonitrile
Benzeneacetonitrile, α-[3-[[2-(3,4-dimethoxyphenyl)ethyl]methylamino]propyl]-3,4,5-trimethoxy-α-(1-methylethyl)-
(±)-α-[3-[(2-(3,4-dimethoxyphenyl)ethyl)methylamino]propyl]-3,4,5-trimethoxy-α-(1-methylethyl)benzeneacetonitrile hydrochloride
D600, Gallopamil, (±)-α-[3-[(2-(3,4-Dimethoxyphenyl)ethyl)methylamino]propyl]-3,4,5-trimethoxy-α-(1-methylethyl)benzeneacetonitrile hydrochloride
[Molecular Formula]

C28H40N2O5
[MDL Number]

MFCD00058000
[MOL File]

16662-47-8.mol
[Molecular Weight]

484.63
Chemical PropertiesBack Directory
[Boiling point ]

605.9±55.0 °C(Predicted)
[density ]

1.068±0.06 g/cm3(Predicted)
[refractive index ]

nD25 1.5402
[storage temp. ]

Store at -20°C
[solubility ]

DMSO: 100 mg/mL (206.34 mM)
[form ]

White to off-white solid.
[pka]

8.96±0.50(Predicted)
[color ]

White to off-white
Safety DataBack Directory
[WGK Germany ]

3
Hazard InformationBack Directory
[Uses]

(±)-Methoxyverapamil hydrochloride has been used:
  • as calcium channel antagonist in Schistosoma mansoni parasite
  • as calcium entry blocker in cultured macrophages
  • in the inhibition of L-type voltage gated Ca2+-channels

[Definition]

ChEBI: Gallopamil is a member of benzenes and an organic amino compound.
[General Description]

Methoxyverapamil is a calmodulin antagonist. It controls flagellar glycoprotein redistribution by modulating calcium signalling. Methoxyverapamil impacts the effect of intracellular calcium levels and affects the sperm capacitation function.
[Biochem/physiol Actions]

Blocks L-type Ca2+ channels
[Side effects]

Gallopamil has a distinctly stronger effect than verapamil but a similar activity profile , .
Spectrum DetailBack Directory
[Spectrum Detail]

METHOXYVERAPAMIL HYDROCHLORIDE(16662-47-8)1HNMR
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