| Identification | Back Directory | [Name]
chlorpromazine N-oxide | [CAS]
1672-76-0 | [Synonyms]
Chlorpromazine oxide
chlorpromazine N-oxide
10H-Phenothiazine-10-propanaMine, 2-chloro-N,N-diMethyl-, N-oxide
3-(2-Chloro-10H-phenothiazin-10-yl)-N,N-dimethylpropan-1-amine oxide | [Molecular Formula]
C17H19ClN2OS | [MOL File]
1672-76-0.mol | [Molecular Weight]
334.86 |
| Chemical Properties | Back Directory | [solubility ]
Chloroform (Slightly), Methanol (Slightly) | [form ]
Solid | [pka]
4.69±0.40(Predicted) | [color ]
Off-White | [Stability:]
Hygroscopic |
| Hazard Information | Back Directory | [Uses]
Chlorpromazine N-Oxide is a metabolite of Chlorpromazine. Chlorpromazine exhibits antiadrenergic, antiserotonergic, anticholinergic, and antihistaminergic properties, and commonly used to treat schizophrenia. | [Definition]
ChEBI: An organochlorine compound that is chlorpromazine in which the acyclic tertiary amino group has been converted into the corresponding N-oxide. | [Metabolic pathway]
When female rats are administered chlorpromazine N-
oxide orally, the metabolites identified in both urine
and feces are chlorpromazine, 7-
hydroxychlorpromazine, chlorpromazine sulfoxide, N-
desmethylchlorpromazine and N-
desmethylchlorpromazine sulfoxide. Chlorpromazine
N-oxide and any metabolite that retains the intact N-
oxide function, such as chlorpromazine N,S-dioxide,
cannot be identified in any of the extracts. |
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