| Identification | Back Directory | [Name]
ETHYLENE GLYCOL DISUCCINATE BIS(SULFO-N- | [CAS]
167410-92-6 | [Synonyms]
Sulfo-EGS Crosslinker
ETHYLENE GLYCOL DISUCCINATE BIS(SULFO-N-
Butanedioic acid, 1,1'-(1,2-ethanediyl) 4,4'-bis(2,5-dioxo-3-sulfo-1-pyrrolidinyl) ester | [Molecular Formula]
C18H20N2O18S2 | [MDL Number]
MFCD00054988 | [MOL File]
167410-92-6.mol | [Molecular Weight]
616.47 |
| Chemical Properties | Back Directory | [density ]
1.85 | [storage temp. ]
−20°C | [form ]
powder | [pka]
-0.34±0.20(Predicted) | [color ]
White to off-white | [Water Solubility ]
water: soluble |
| Hazard Information | Back Directory | [Uses]
Sulfo-EGS is a homobifunctional, amine-reactive chemical crosslinker. Sulfo-EGS is used to study protein-protein or protein-peptide interactions, which can determine the spatial proximity of amino acid residues in a protein complex, without relying on standards[1]. | [reaction suitability]
reagent type: cross-linking reagent | [References]
[1] Kalkhof S, et al., Chemical cross-linking and high-performance Fourier transform ion cyclotron resonance mass spectrometry for protein interaction analysis: application to a calmodulin/target peptide complex. Anal Chem. 2005 Jan 15;77(2):495-503. DOI:10.1021/ac0487294 |
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