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1680193-80-9

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1680193-80-9 Structure

1680193-80-9 Structure
IdentificationBack Directory
[Name]

JZP 361
[CAS]

1680193-80-9
[Synonyms]

JZP 361
[4-(8-Chloro-5,6-dihydro-11H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ylidene)-1-piperidinyl](1H-1,2,4-triazol-1-yl)methanone
[Molecular Formula]

C22H20ClN5O
[MDL Number]

MFCD30536369
[MOL File]

1680193-80-9.mol
[Molecular Weight]

405.88
Chemical PropertiesBack Directory
[Melting point ]

177-177.9°C
[Boiling point ]

611.7±65.0 °C(Predicted)
[density ]

1.41±0.1 g/cm3(Predicted)
[storage temp. ]

-20°C Freezer, Under inert atmosphere
[solubility ]

Chloroform (Slightly), Ethyl Acetate (Slightly)
[form ]

Solid
[pka]

4.12±0.20(Predicted)
[color ]

White to Off-White
Hazard InformationBack Directory
[Uses]

JZP 361 is a potent and reversible inhibitor of human recombinant MAGL (hMAGL, IC50 = 46 nM).
[IC 50]

hMAGL: 46 nM (IC50); hABHD6: 1.79 μM (IC50); hFAAH: 7.24 μM (IC50); H1 Receptor: 6.81 (pA2)
[storage]

Store at -20°C
Spectrum DetailBack Directory
[Spectrum Detail]

JZP 361(1680193-80-9)1HNMR
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