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1680205-79-1

1680205-79-1 Structure

1680205-79-1 Structure
IdentificationBack Directory
[Name]

ELA-32 (human)
[CAS]

1680205-79-1
[Synonyms]

ELA-32 (human)
Chemical PropertiesBack Directory
[storage temp. ]

Store at -20°C
[solubility ]

Soluble in DMSO
[form ]

Solid
[color ]

White to off-white
[Sequence]

Gln-Arg-Pro-Val-Asn-Leu-Thr-Met-Arg-Arg-Lys-Leu-Arg-Lys-His-Asn-Cys-Leu-Gln-Arg-Arg-Cys-Met-Pro-Leu-His-Ser-Arg-Val-Pro-Phe-Pro (Disulfide bridge: Cys17-Cys22)
Hazard InformationBack Directory
[Uses]

ELA-32 (human) is a potent critical cardiac developmental peptide that acts through the G-protein–coupled apelin receptor[1].
[References]

[1] Yang P, et al. Elabela/Toddler Is an Endogenous Agonist of the Apelin APJ Receptor in the Adult Cardiovascular System, and Exogenous Administration of the Peptide Compensates for the Downregulation of Its Expression in Pulmonary Arterial Hypertension. Circulation. 2017;135(12):1160-1173. DOI:10.1161/CIRCULATIONAHA.116.023218
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