| Hazard Information | Back Directory | [Description]
L 748780 is a selective inhibitor of inducible COX-2. | [Uses]
L 748780 (compound 2) is a selectivity COX-2 inhibitor with the IC50 values of 0.5 μM and ＞ 100 μM for COX-2 and COX-1, respectively[1]. | [IC 50]
COX-2: 0.5 μM (IC50); COX-1: > 100 μM (IC50) | [References]
[1] Lau CK, et al. From indomethacin to a selective COX-2 inhibitor. Development of indolalkanoic acids as potent and selective cyclooxygenase-2 inhibitors. Adv Exp Med Biol. 1997;407:73-8. PMID: 9321934. PMID:9321934 |
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