1688684-07-2

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1688684-07-2 Structure

Identification	Back Directory
[Name] 5-[[[(3-Chloro-4-fluorophenyl)sulfonyl]amino]methyl]-N-[(2-methyl-5-thiazolyl)methyl]-2-pyrazinecarboxamide
[CAS] 1688684-07-2
[Synonyms] 5-[[[(3-Chloro-4-fluorophenyl)sulfonyl]amino]methyl]-N-[(2-methyl-5-thiazolyl)methyl]-2-pyrazinecarboxamide
[Molecular Formula] C17H15ClFN5O3S2
[MOL File] 1688684-07-2.mol
[Molecular Weight] 455.92

Chemical Properties	Back Directory
[density ] 1.502±0.06 g/cm3(Temp: 20 °C; Press: 760 Torr)(Predicted)
[pka] 7.58±0.50(Predicted)

Hazard Information	Back Directory
[Uses] MPX-004 is a potent GluN2A antagonist. MPX-004 inhibits GluN2A-containing NMDA receptors expressed in HEK cells with an IC50 of 79 nM. MPX-004 has no inhibitory effect on GluN2B or GluN2D receptor-mediated responses. MPX-004 has the potential for neuropsychiatric and developmental disorders research[1].
[IC 50] NMDA Receptor
[References] [1] Robert A Volkmann, et al. MPX-004 and MPX-007: New Pharmacological Tools to Study the Physiology of NMDA Receptors Containing the GluN2A Subunit. PLoS One. 2016 Feb 1;11(2):e0148129. DOI:10.1371/journal.pone.0148129

1688684-07-2 suppliers list

Company Name:	Jiangsu Aikon Biopharmaceutical R&D Co.,Ltd
Tel:	025-58851090 17714375163
Website:	https://www.aikonchem.com/

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