| Identification | Back Directory | [Name]
CASPASE-3 | [CAS]
169592-56-7 | [Synonyms]
YAMA
CPP32
CPP321
CASP-3
APOPAIN
CASPASE-3
YAMA HUMAN
CPP32 HUMAN
PROCASPASE-3
APOPAIN HUMAN
HUMAN CASPASE-3
CASPASE-3, HUMAN
Apopain precursor
CPP32, ACTIVE FORM
CASPASE-3 PRECURSOR
PROCASPASE-3 (HUMAN)
CASPASE-3, ACTIVE FORM
Apopain, CPP32, Yama
Cysteine protease CPP32
CASPASE-3 (HUMAN) (REC)
PRO-CASPASE-3 (HUMAN) (REC)
Human CASP3 Protein, His Tag
PROCASPASE-3, HIS TAG(R) HUMAN
PROCASPASE-3, HIS TAG(R), MOUSE
CASPASE-3 (HUMAN) (RECOMBINANT)
CASPASE-3 (HUMAN) (ACTIVE) (REC)
PRO-CASPASE-3 (HUMAN) (RECOMBINANT)
CASPASE-3, HUMAN, RECOMBINANT, E COLI
CASPASE-3 (ACTIVE) (HUMAN) (RECOMBINANT)
PROCASPASE-3, HUMAN, RECOMBINANT, E COLI
CASPASE-3 (HUMAN) (ACTIVE) (RECOMBINANT)
Anti-CSPN3 (Cleaved-Asp175) antibody produced in rabbit
ANTI-CLEAVED-CASP3 (ASP175) antibody produced in rabbit
Anti-CASP3 (p17, Cleaved-Asp175) antibody produced in rabbit | [MDL Number]
MFCD01634593 |
| Chemical Properties | Back Directory | [Melting point ]
127 °C | [storage temp. ]
−70°C | [solubility ]
PBS: soluble | [form ]
buffered aqueous glycerol solution | [biological source]
rabbit | [Specific Activity]
≥1450units/μg protein |
| Hazard Information | Back Directory | [Uses]
Caspase 3 human has been used to digest human r-vimentin. It has also been used in caspase-3 inhibition assay and protease inhibition assay. | [General Description]
Human recombinant C-terminal histidine tagged caspase 3 is a fully active protein consisting of 17 kDa and 13.5 kDa subunits; the 13.5 kDa subunit contains the histidine tag. | [Biochem/physiol Actions]
Caspase 3 is a member of the CED-3 subfamily of caspases and is responsible for the cleavage of many key proteins such as the nuclear enzyme poly(ADP-ribose) polymerase (PARP), the inhibitor of caspase-activated deoxyribonuclease (ICAD), and gelsolin, a protein involved in apoptosis regulation. Caspase?3 is considered to be an effector caspase, activating pro-caspase?6 and pro-caspase?9 in vitro. Caspase 3 can be activated by caspase 8, caspase 6, and granzyme B. |
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| Company Name: |
Sigma-Aldrich
|
| Telephone: |
021-61415566 800-8193336 |
| Website: |
https://www.sigmaaldrich.cn |
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