| Identification | Back Directory | [Name]
Benzaldehyde, 3-bromo-4-(dipropylamino)- | [CAS]
1695970-90-1 | [Synonyms]
ALDH1A3-IN-1
Benzaldehyde, 3-bromo-4-(dipropylamino)- | [Molecular Formula]
C13H18BrNO | [MOL File]
1695970-90-1.mol | [Molecular Weight]
284.19 |
| Chemical Properties | Back Directory | [Boiling point ]
367.4±32.0 °C(Predicted) | [density ]
1.284±0.06 g/cm3(Predicted) | [storage temp. ]
4°C, protect from light | [form ]
Liquid | [pka]
1.63±0.50(Predicted) | [color ]
Light yellow to yellow |
| Hazard Information | Back Directory | [Uses]
ALDH1A3-IN-1 (Compound 14) is a potent ALDH1A3 inhibitor, with an IC50 of 0.63 μM and a Ki of 0.46 μM. ALDH1A3-IN-1 can be studied in prostate cancer[1]. | [IC 50]
ALDH1; ALDH1A3: 0.63 μM (IC50); ALDH1A1: 7.08 μM (IC50); ALDH3A1: 8.00 μM (IC50); ALDH1A3: 0.46 μM (Ki); ALDH1A3: 26.92 μM (Km) | [References]
[1] Ali I M Ibrahim, et al. Expansion of the 4-(Diethylamino)benzaldehyde Scaffold to Explore the Impact on Aldehyde Dehydrogenase Activity and Antiproliferative Activity in Prostate Cancer. J Med Chem. 2022 Mar 10;65(5):3833-3848. DOI:10.1021/acs.jmedchem.1c01367 |
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