ChemicalBook--->CAS DataBase List--->16981-20-7

16981-20-7

16981-20-7 Structure

16981-20-7 Structure
IdentificationBack Directory
[Name]

Mesuol
[CAS]

16981-20-7
[Synonyms]

Mesuol
5,7-Dihydroxy-6-isobutyryl-8-(3-methyl-2-butenyl)-4-phenylcoumarin
5,7-dihydroxy-6-isobutyryl-8-(3-methylbut-2-enyl)-4-phenyl-2H-chromen-2-one
5,7-dihydroxy-8-(3-methylbut-2-enyl)-6-(2-methylpropanoyl)-4-phenylchromen-2-one
5,7-Dihydroxy-8-(3-methyl-2-butenyl)-6-(2-methylpropanoyl)-4-phenyl-2H-1-benzopyran-2-one
5,7-Dihydroxy-8-(3-methyl-2-butenyl)-6-(2-methyl-1-oxopropyl)-4-phenyl-2H-1-benzopyran-2-one
2H-1-Benzopyran-2-one, 5,7-dihydroxy-8-(3-methyl-2-buten-1-yl)-6-(2-methyl-1-oxopropyl)-4-phenyl-
[Molecular Formula]

C24H24O5
[MDL Number]

MFCD28009398
[MOL File]

16981-20-7.mol
[Molecular Weight]

392.44
Chemical PropertiesBack Directory
[Melting point ]

171℃
[Boiling point ]

190-200 °C
[density ]

1.238±0.06 g/cm3(Predicted)
[pka]

5.31±0.20(Predicted)
[LogP]

8.930 (est)
Hazard InformationBack Directory
[Description]

Mesuol is a coumarin isolated from the stem bark of Mesua borneensis, which displays antimalarial and antioxidant activities. Mesuol was shown to inhibit HIV-1 replication by targeting the NF-kappaB pathway.
[Uses]

Mesuol, a natural product isolated from M. ferrea L. seed oil, has antioxidant and immunomodulatory effects[1].
[Definition]

ChEBI: Mesuol is a neoflavonoid.
[References]

[1] Manoj Kumar Chahar, et al. In-vivo antioxidant and immunomodulatory activity of mesuol isolated from Mesua ferrea L. seed oil. Int Immunopharmacol. 2012 Aug;13(4):386-91. DOI:10.1016/j.intimp.2012.05.006
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