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169815-40-1

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169815-40-1 Structure

169815-40-1 Structure
IdentificationBack Directory
[Name]

AQ-13
[CAS]

169815-40-1
[Synonyms]

AQ-13
AQ-13 dihydrochloride
N-(7-chloroquinolin-4-yl)-N',N'-diethylpropane-1,3-diamine
[Molecular Formula]

C16H24Cl3N3
[MOL File]

169815-40-1.mol
[Molecular Weight]

328.28
Chemical PropertiesBack Directory
[storage temp. ]

Store at -20°C
[solubility ]

DMSO : 80 mg/mL (219.33 mM)
[form ]

Solid
[color ]

Light yellow to yellow
Hazard InformationBack Directory
[Uses]

AQ-13 dihydrochloride is an aminoquinoline antimalarial agent that is effective against drug-resistant strains of Plasmodium falciparum.
[in vivo]

Slight decreases in the PCE/RBC ratio are observed in male and female rats treated with CQ and in females only treated with AQ-13; however, none of these changes is statistically significant[1].

[IC 50]

Plasmodium
[References]

[1] Riccio ES, et al. Genetic toxicology testing of the antimalarial drugs chloroquine and a new analog, AQ-13. Environ Mol Mutagen. 2001;38(1):69-79. DOI:10.1002/em.1052
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