ChemicalBook--->CAS DataBase List--->1699735-80-2

1699735-80-2

1699735-80-2 Structure

1699735-80-2 Structure
IdentificationBack Directory
[Name]

3A-MPLA
[CAS]

1699735-80-2
[Synonyms]

[Molecular Formula]

C54H106N3O17P
[MOL File]

1699735-80-2.mol
[Molecular Weight]

1100.42
Chemical PropertiesBack Directory
[storage temp. ]

-20°C
[form ]

powder
Hazard InformationBack Directory
[Uses]

vaccine development
[Biological Activity]

Monophosphoryl lipid A (MPLA) is a natural agonist for the toll-like receptor-4 (TLR4). It is useful as an adjuvant in immunization. MPLA is a safe prophylactic agent and has immunotherapeutic applications. It induces tumor necrosis factor and interleukin (IL)-1βhowever not as efficient as lipopolysaccharide (LPS). MPLA improves immune response during bacterial sepsis infection.
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