| Identification | Back Directory | [Name]
HEXADECENOIC ACID | [CAS]
17004-51-2 | [Synonyms]
sapienic acid
cis-6-Hexadecenoic Acid
6-Hexadecenoic acid, (6Z)- | [Molecular Formula]
C16H30O2 | [MDL Number]
MFCD16620985 | [MOL File]
17004-51-2.mol | [Molecular Weight]
254.41 |
| Chemical Properties | Back Directory | [Boiling point ]
369.8±11.0 °C(Predicted) | [density ]
0.905±0.06 g/cm3(Predicted) | [storage temp. ]
Store at -20°C | [solubility ]
Chloroform: soluble; Ethanol: soluble; Ether: soluble; Methanol: soluble | [pka]
4.75±0.10(Predicted) | [Cosmetics Ingredients Functions]
SKIN CONDITIONING - EMOLLIENT
SKIN CONDITIONING |
| Hazard Information | Back Directory | [Uses]
Sapienic acid is a fatty acid commonly found on the skin and in mucosa. Sapienic acid has variable antimicrobial activities against Gram-positive and Gram-negative bacteria found on the skin and in the oral cavity. Sapienic acid is active against Streptococcus sanguinis, Streptococcus mitis and Fusobacterium nucleatum with MBC values of 31.3 μg/mL, 375.0 μg/mL and 93.8 μg/mL, respectively[1]. | [Definition]
ChEBI: A hexadecenoic acid in which the double bond is located at position 6 (the Z-geoisomer). A major component of human sebaceous lipids that is involved in skin self-sterilisation and atopic dermatitis amelioration. | [storage]
Store at -20°C | [References]
[1] Fischer CL, et al. Antibacterial activity of sphingoid bases and fatty acids against Gram-positive and Gram-negative bacteria. Antimicrob Agents Chemother. 2012 Mar;56(3):1157-61. DOI:10.1128/AAC.05151-11 |
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