| Identification | Back Directory | [Name]
PI3Kδ-IN-2 | [CAS]
1702816-75-8 | [Synonyms]
YY-20394
PI3K&delta
PI3K|A-IN-2
Linperlisib
PI3Kδ inhibitor 2
Linperlisib free base
Linperlisib (YY-20394)
YY-20394;YY 20394;YY20394
Methanesulfonamide, N-[5-[6-fluoro-8-[[4-(1-hydroxy-1-methylethyl)-1-piperidinyl]methyl]-2-(4-morpholinyl)-4-quinazolinyl]-2-methoxy-3-pyridinyl]- | [Molecular Formula]
C28H37FN6O5S | [MOL File]
1702816-75-8.mol | [Molecular Weight]
588.69 |
| Chemical Properties | Back Directory | [Boiling point ]
742.4±70.0 °C(Predicted) | [density ]
1.355±0.06 g/cm3(Predicted) | [storage temp. ]
Store at -20°C | [solubility ]
DMSO:100.0(Max Conc. mg/mL);169.87(Max Conc. mM) | [form ]
Solid | [pka]
5.81±0.50(Predicted) | [color ]
Light yellow to yellow |
| Hazard Information | Back Directory | [Uses]
Linperlisib (YY-20394) is a potent, orally bioavailable and selective inhibitor of PI3Kδ extracted from patent WO 2015055071 A1, compound 10; has an IC50 of 6.4 nM[1]. | [IC 50]
PI3Kδ: 6.4 nM (IC50) | [storage]
Store at -20°C | [References]
[1] WO 2015055071 A1 |
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