| Identification | Back Directory | [Name]
Acetamide, N-[2-(2,3,7,8-tetrahydro-1H-furo[2,3-g]indol-1-yl)ethyl]- | [CAS]
170729-12-1 | [Synonyms]
429
GR196
GR-196
GR 196
GR196429
GR-196429
GR 196429
Acetamide, N-[2-(2,3,7,8-tetrahydro-1H-furo[2,3-g]indol-1-yl)ethyl]- | [Molecular Formula]
C14H18N2O2 | [MDL Number]
MFCD00940454 | [MOL File]
170729-12-1.mol | [Molecular Weight]
246.3 |
| Hazard Information | Back Directory | [Description]
GR 196429 is a melatonin receptor agonist with some selectivity for the MT1 subtype. Studies in mice have shown GR-196,429 to produce both sleep-promoting effects and alterations of circadian rhythm, as well as stimulating melatonin release. | [Uses]
GR 196429 is a melatonin receptor agonist with some selectivity for the MT1 subtype. GR 196429 produces both sleep-promoting effects and alterations of circadian rhythm, as well as stimulating melatonin release in mice[1]. | [References]
[1] I J Beresford, et al. Pharmacological characterisation of melatonin mt1 receptor-mediated stimulation of [35S]-GTPgammaS binding. Biochem Pharmacol. 1998 Nov 1;56(9):1167-74. DOI:10.1016/s0006-2952(98)00254-8 |
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