| Identification | Back Directory | [Name]
Benzenesulfonamide, 4-chloro-N-[3-[(4-chlorophenyl)amino]-1H-1,2,4-triazol-5-yl]-2-mercapto-5-methyl- | [CAS]
170747-33-8 | [Synonyms]
NSC666715
Benzenesulfonamide, 4-chloro-N-[3-[(4-chlorophenyl)amino]-1H-1,2,4-triazol-5-yl]-2-mercapto-5-methyl- | [Molecular Formula]
C15H13Cl2N5O2S2 | [MOL File]
170747-33-8.mol | [Molecular Weight]
430.33 |
| Hazard Information | Back Directory | [Uses]
NSC666715 is a strand-displacement activity of DNA polymerase inhibitor. NSC666715 potentiates Temozolomide (HY-17364)-induced DNA damage, cell senescence and apoptosis. NSC666715 can be used for study colorectal cancer[1]. | [References]
[1] Jaiswal AS, et al. NSC666715 and Its Analogs Inhibit Strand-Displacement Activity of DNA Polymerase β and Potentiate Temozolomide-Induced DNA Damage, Senescence and Apoptosis in Colorectal Cancer Cells. PLoS One. 2015;10(5):e0123808. Published 2015 May 1. DOI:10.1371/journal.pone.0123808 |
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