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170871-87-1

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170871-87-1 Structure

170871-87-1 Structure
IdentificationBack Directory
[Name]

N6-Benzoyl-3'-deoxy-5'-O-(4,4'-dimethoxytrityl)-3'-fluoroadenosine
[CAS]

170871-87-1
[Synonyms]

5'-O-DMTr-3'-F-N2-Bz-3'-deoxy-Adenosine
N6-Benzoyl-3'-deoxy-5'-O-DMT-3'-fluoroadenosine
N6-Benzoyl-3'-deoxy-5'-O-(4,4'-dimethoxytrityl)-3'-fluoroadenosine
N6-Benzoyl-3’-deoxy-5’-O-(4,4’-dimethoxytrityl)-3’-fluoroadenosine
Adenosine, N-benzoyl-5'-O-[bis(4-methoxyphenyl)phenylmethyl]-3'-deoxy-3'-fluoro- (9CI)
[Molecular Formula]

C38H34FN5O6
[MDL Number]

MFCD31537282
[MOL File]

170871-87-1.mol
[Molecular Weight]

675.72
Chemical PropertiesBack Directory
[density ]

1.35±0.1 g/cm3(Predicted)
[pka]

7.87±0.43(Predicted)
Hazard InformationBack Directory
[Uses]

N6-Benzoyl-3'-deoxy-5'-O-DMT-3'-fluoroadenosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
[References]

[1] Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88. DOI:10.2174/138161212801227005
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