| Identification | Back Directory | [Name]
1-vinylpyrene | [CAS]
17088-21-0 | [Synonyms]
3-Vinylpyrene
1-vinylpyrene
1-ethenylpyrene
Pyrene, 1-ethenyl | [Molecular Formula]
C18H12 | [MDL Number]
MFCD00029253 | [MOL File]
17088-21-0.mol | [Molecular Weight]
228.29 |
| Chemical Properties | Back Directory | [Melting point ]
87-89 °C | [Boiling point ]
305.1°C (rough estimate) | [density ]
1.1209 (estimate) | [refractive index ]
1.5500 (estimate) | [form ]
Solid | [color ]
White to off-white |
| Hazard Information | Back Directory | [Uses]
1-Ethenylpyrene (1-Vinylpyrene) is an anti-chemical carcinogen that inhibits the formation of skin tumors initiated by either DMBA (HY-W011845) or Benzo[a]pyrene (HY-107377)[1]. | [in vivo]
Application of 44 nmol of 1-Ethenylpyrene (1-Vinylpyrene) inhibits tumor initiation by 10 nmol of DMBA approximately 30%; application of 4.4 μmol of 1-Ethenylpyrene (1-Vinylpyrene) inhibits tumor initiation by 200 nmol of Benzo[a]pyrene approximately 56%[1]. | [References]
[1] W L Alworth, et al. Potent inhibitory effects of suicide inhibitors of P450 isozymes on 7,12-dimethylbenz[a]anthracene and benzo[a]pyrene initiated skin tumors. Carcinogenesis. 1991 Jul;12(7):1209-15. DOI:10.1093/carcin/12.7.1209 |
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