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171277-06-8

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171277-06-8 Structure

171277-06-8 Structure
IdentificationBack Directory
[Name]

Phenol, 3-[[[2-[4-hydroxy-5-methyl-2-(1-methylethyl)phenoxy]ethyl]methylamino]methyl]-4-methoxy-2,5,6-trimethyl-
[CAS]

171277-06-8
[Synonyms]

JTH-601 free base
JTH 601 free base,JTH601 free base
Phenol, 3-[[[2-[4-hydroxy-5-methyl-2-(1-methylethyl)phenoxy]ethyl]methylamino]methyl]-4-methoxy-2,5,6-trimethyl-
[Molecular Formula]

C24H35NO4
[MOL File]

171277-06-8.mol
[Molecular Weight]

401.55
Chemical PropertiesBack Directory
[Boiling point ]

570.0±50.0 °C(Predicted)
[density ]

1.094±0.06 g/cm3(Predicted)
[pka]

10.72±0.25(Predicted)
Hazard InformationBack Directory
[Uses]

JTH-601 Free base is a novel alpha1-adrenoceptor antagonist that exhibits potent activity in inhibiting phenylephrine-induced contractions in lower urinary tract tissues. JTH-601 Free base competitively antagonizes alpha1-adrenoceptor-mediated contractile responses, demonstrating greater potency than prazosin or tamsulosin. JTH-601 Free base is anticipated to be effective in treating urinary outlet obstruction associated with benign prostatic hyperplasia.
[References]

[1] Effect of JTH-601, a novel alpha1-adrenoceptor antagonist, on the function of lower urinary tract and blood pressure DOI:10.1016/s0014-2999(99)00344-1
171277-06-8 suppliers list
Company Name: TargetMol Chemicals Inc.  
Telephone: 15002134094
Website: https://www.targetmol.cn/
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51384-51-1 3616-04-4 223673-61-8 42200-33-9 18559-94-9 72795-01-8