| Identification | Back Directory | [Name]
Benzoic acid, 4-[[4-[(Z)-[3-(2-methylphenyl)-4-oxo-2-thioxo-5-thiazolidinylidene]methyl]phenoxy]methyl]- | [CAS]
1715076-35-9 | [Synonyms]
JHN76359
Slingshot inhibitor D3
Slingshot inhibitor D3，JHN76359
Benzoic acid, 4-[[4-[(Z)-[3-(2-methylphenyl)-4-oxo-2-thioxo-5-thiazolidinylidene]methyl]phenoxy]methyl]- | [Molecular Formula]
C25H19NO4S2 | [MDL Number]
MFCD34567264 | [MOL File]
1715076-35-9.mol | [Molecular Weight]
461.55 |
| Chemical Properties | Back Directory | [Boiling point ]
667.4±65.0 °C(Predicted) | [density ]
1.44±0.1 g/cm3(Predicted) | [form ]
Solid | [pka]
4.15±0.10(Predicted) | [color ]
Light yellow to yellow |
| Hazard Information | Back Directory | [Description]
JHN76359, also known as Slingshot inhibitor D3, is a novel Potent Inhibitor of the Protein Phosphatase Slingshot. This compound was first reported in ChemMedChem (2015), 10(12), 1980-1987 This product has no formal name at the moment. | [Uses]
Slingshot inhibitor D3 is a potent, selective, reversible and competitive inhibitor of Slingshot. The IC50 value for Slingshot 1 is 3 μM and the Ki value for Slingshot 2 is 3.9 μM. Slingshot inhibitor D3 has similar inhibitory activities toward both Slingshot 1 and Slingshot 2[1]. | [References]
[1] Li KS, et al. Identification of para-Substituted Benzoic Acid Derivatives as Potent Inhibitors of the Protein Phosphatase Slingshot. ChemMedChem. 2015;10(12):1980-1987. DOI:10.1002/cmdc.201500454 |
|
|