| Identification | Back Directory | [Name]
5’-O-TBDPS-5-methyl-2,2’-anhydrouridine | [CAS]
171763-19-2 | [Synonyms]
5’-O-TBDPS-5-methyl-2,2’-anhydrouridine
5’-O-TBDPS-5-methyl-2,2’-anhydrouridine
6H-Furo[2',3':4,5]oxazolo[3,2-a]pyrimidin-6-one, 2-[[[(1,1-dimethylethyl)diphenylsilyl]oxy]methyl]-2,3,3a,9a-tetrahydro-3-hydroxy-7-methyl-, (2R,3R,3aS,9aR)- | [Molecular Formula]
C26H30N2O5Si | [MDL Number]
MFCD32215224 | [MOL File]
171763-19-2.mol | [Molecular Weight]
478.61 |
| Hazard Information | Back Directory | [Uses]
5’-O-TBDPS-5-methyl-2,2’-anhydrouridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1]. | [References]
[1] Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88. DOI:10.2174/138161212801227005 |
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