ChemicalBook--->CAS DataBase List--->171783-05-4

171783-05-4

171783-05-4 Structure

171783-05-4 Structure
IdentificationBack Directory
[Name]

CROSSTIDE
[CAS]

171783-05-4
[Synonyms]

Crosstide >=97% (HPLC), lyophilized powder
Glycine, glycyl-L-arginyl-L-prolyl-L-arginyl-L-threonyl-L-seryl-L-seryl-L-phenylalanyl-L-alanyl-L-a-glutaMyl-
Glycine, glycyl-L-arginyl-L-prolyl-L-arginyl-L-threonyl-L-seryl-L-seryl-L-phenylalanyl-L-alanyl-L-α-glutamyl-
[Molecular Formula]

C48H77N17O17
[MDL Number]

MFCD03787963
[MOL File]

171783-05-4.mol
[Molecular Weight]

1164.23
Chemical PropertiesBack Directory
[storage temp. ]

−20°C
[solubility ]

H2O: soluble
[form ]

lyophilized powder
[color ]

White to off-white
[Sequence]

Gly-Arg-Pro-Arg-Thr-Ser-Ser-Phe-Ala-Glu-Gly
Safety DataBack Directory
[Safety Statements ]

22-24/25
[WGK Germany ]

3
Hazard InformationBack Directory
[Uses]

Crosstide is a peptide analog of glycogen synthase kinase α/β fusion protein sequence which is a substrate for Akt.
[References]

[1] Bentley JK, et al. Rhinovirus activates interleukin-8 expression via a Src/p110beta phosphatidylinositol 3-kinase/Akt pathway in human airway epithelial cells. J Virol. 2007 Feb;81(3):1186-94. Epub 2006 Nov 22. DOI:10.1128/JVI.02309-06
[2] Baer K, et al. Activation of a GST-tagged AKT2/PKBbeta. Biochim Biophys Acta. 2005 Oct 10;1725(3):340-7. Epub 2005 Apr 20. DOI:10.1016/j.bbagen.2005.04.002
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