| Identification | Back Directory | [Name]
(3aS,4S,6aR)-4-(4-aminobutyl)tetrahydro-1H-thieno[3,4-d]imidazol-2(3H)-one | [CAS]
173401-47-3 | [Synonyms]
Norbiotinamine
(3aS,4S,6aR)-4-(4-aminobutyl)tetrahydro-1H-thieno[3,4-d]imidazol-2(3H)-one
1H-Thieno[3,4-d]imidazol-2(3H)-one, 4-(4-aminobutyl)tetrahydro-, (3aS,4S,6aR)- | [Molecular Formula]
C9H17N3OS | [MDL Number]
MFCD34469943 | [MOL File]
173401-47-3.mol | [Molecular Weight]
215.32 |
| Chemical Properties | Back Directory | [Boiling point ]
478.0±30.0 °C(Predicted) | [density ]
1.162±0.06 g/cm3(Predicted) | [storage temp. ]
4°C, protect from light | [solubility ]
H2O : 200 mg/mL (928.85 mM; ultrasonic and warming and heat to 60°C) | [form ]
Solid | [pka]
13.90±0.40(Predicted) | [color ]
White to off-white |
| Hazard Information | Back Directory | [Uses]
Norbiotinamine is an alternative to biotin. Norbiotinamine can be coupled with a carboxylic group of amino acids to give inverse peptides, having the amide linkage oriented in the opposite direction[1]. | [storage]
4°C, protect from light | [References]
[1] Szalecki W.Synthesis of?Norbiotinamine?and its derivatives. Bioconjug Chem.?1996 Mar-Apr;7(2):271-3. DOI:10.1021/bc950094f
[2] Zhou GC,?et al. Design, synthesis and evaluation of a cellular stable and detectable biotinylated fumagillin probe and investigation of cell permeability of fumagillin and its analogs to endothelial and cancer cells.Eur J Med Chem.?2013;70:631-9. DOI:10.1016/j.ejmech.2013.10.033 |
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