| Identification | Back Directory | [Name]
(E)-4-[2-{2-[N-(4-Methoxybenzenesulfonyl)aMino]phenyl}ethenyl ]pyridine | [CAS]
173528-92-2 | [Synonyms]
HMN-154;HMN 154;HMN154
2 AMINO 4 METHYL PYRIDINE AMINO PYRIDIN E
(E)-4-[2-{2-[N-(4-Methoxybenzenesulfonyl)aMino]phenyl}ethenyl ]pyridine
Benzenesulfonamide, 4-methoxy-N-[2-[(1E)-2-(4-pyridinyl)ethenyl]phenyl]- | [Molecular Formula]
C20H18N2O3S | [MOL File]
173528-92-2.mol | [Molecular Weight]
366.43 |
| Chemical Properties | Back Directory | [Boiling point ]
553.7±60.0 °C(Predicted) | [density ]
1.313±0.06 g/cm3(Predicted) | [storage temp. ]
Sealed in dry,Room Temperature | [solubility ]
DMSO:15.0(Max Conc. mg/mL);40.93(Max Conc. mM) | [form ]
Solid | [pka]
8.09±0.10(Predicted) | [color ]
White to off-white |
| Hazard Information | Back Directory | [Uses]
HMN-154 is a novel benzenesulfonamide anticancer compound; inhibits KB and colon38 cells with IC50 values of 0.0026 and 0.003 μg/mL, respectively. | [References]
[1] Tanaka H, et al. Isolation of cDNAs encoding cellular drug-binding proteins using a novel expression cloning procedure: drug-western. Mol Pharmacol. 1999 Feb;55(2):356-63. DOI:10.1124/mol.55.2.356 |
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