ChemicalBook--->CAS DataBase List--->173662-97-0

173662-97-0

173662-97-0 Structure

173662-97-0 Structure
IdentificationBack Directory
[Name]

N-methyl-alpha-methoxy-2-[(2,5-dimethylphenoxy)methyl]phenylacetamide
[CAS]

173662-97-0
[Synonyms]

MANDESTROBIN
Mandestrobin Standard
Benzeneacetamide, 2-[(2,5-dimethylphenoxy)methyl]-α-methoxy-N-methyl-
Benzeneacetamide, 2-[(2,5-dimethylphenoxy)methyl]-α-methoxy-N-methyl-
2-(2-((2,5-dimethylphenoxy)methyl)phenyl)-2-methoxy-N-methylacetamide
N-methyl-alpha-methoxy-2-[(2,5-dimethylphenoxy)methyl]phenylacetamide
[Molecular Formula]

C19H23NO3
[MOL File]

173662-97-0.mol
[Molecular Weight]

313.39
Chemical PropertiesBack Directory
[Boiling point ]

488.1±45.0 °C(Predicted)
[density ]

1.097±0.06 g/cm3(Predicted)
[solubility ]

Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly)
[form ]

Solid
[pka]

14.62±0.46(Predicted)
[color ]

Off-White to Pale Yellow
[Henry's Law Constant]

1.5×106 mol/(m3Pa) at 25℃, Maniere et al. (2011)
[LogP]

3.775(25℃)
[EPA Substance Registry System]

Benzeneacetamide, 2-[(2,5-dimethylphenoxy)methyl]-.alpha.-methoxy-N-methyl- (173662-97-0)
Safety DataBack Directory
[Symbol(GHS) ]

Environment (GHS09)
GHS09
[Signal word ]

Warning
[Hazard statements ]

H410
[Precautionary statements ]

P273-P391-P501
Hazard InformationBack Directory
[Uses]

Mandestrobin is a novel fungicide having a methoxyacetamid structure. Mandestrobin also shows safer profiles for human health and the environment.
[Definition]

ChEBI:2-{2-[(2,5-dimethylphenoxy)methyl]phenyl}-2-methoxy-N-methylacetamide is a monocarboxylic acid amide obtained by formal condensation of the carboxy group of {2-[(2,5-dimethylphenoxy)methyl]phenyl}(methoxy)acetic acid with the amino group of methylamine. It is a monocarboxylic acid amide and an aromatic ether.
[Production Methods]

Mandestrobin is produced commercially through a strobilurin-type synthetic route that assembles its methoxyacrylate fungicide framework. Industrial synthesis begins with preparation of a substituted benzyl alcohol intermediate, which is functionalised via etherification to introduce the oxymethyl linkage. In parallel, a methoxyiminoacetic acid derivative is synthesised to provide the characteristic methoxyacrylate moiety. These fragments are then coupled under controlled esterification conditions to yield the final mandestrobin structure.
[Mechanism of action]

Quinone Outside Inhibitor (QoI).
[Pesticide Type]

Fungicide
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