| Identification | Back Directory | [Name]
2'-Amino-2'-deoxy-5'-O-(4,4'-dimethoxytrityl)uridine | [CAS]
174221-86-4 | [Synonyms]
2'-Amino-2'-deoxy-5'-O-DMT-uridine
2'-Amino-2'-deoxy-5'-O-(4,4'-dimethoxytrityl)uridine
Uridine, 2'-amino-5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-deoxy- | [Molecular Formula]
C30H31N3O7 | [MDL Number]
MFCD30570243 | [MOL File]
174221-86-4.mol | [Molecular Weight]
545.58 |
| Hazard Information | Back Directory | [Uses]
2′-Amino-5′-O-[bis(4-methoxyphenyl)phenylmethyl]-2′-deoxyuridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1]. | [References]
[1] Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88. DOI:10.2174/138161212801227005 |
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