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174232-44-1

174232-44-1 Structure

174232-44-1 Structure
IdentificationBack Directory
[Name]

Androst-11-ene-14-carboxylic acid, 3-(acetyloxy)-4,4,8,12,16-pentamethyl-15,17-dioxo-, methyl ester, (3β,5β,8α,9β,10α,13α)-
[CAS]

174232-44-1
[Synonyms]

Androst-11-ene-14-carboxylic acid, 3-(acetyloxy)-4,4,8,12,16-pentamethyl-15,17-dioxo-, methyl ester, (3β,5β,8α,9β,10α,13α)-
[Molecular Formula]

C28H40O6
[MOL File]

174232-44-1.mol
[Molecular Weight]

472.62
Chemical PropertiesBack Directory
[Boiling point ]

532.5±50.0 °C(Predicted)
[density ]

1.15±0.1 g/cm3(Predicted)
[pka]

9.07±0.70(Predicted)
Hazard InformationBack Directory
[Uses]

Andrastin B is a protein farnesyltransferase inhibitor. Andrastin B has a common androstane skeleton[1].
[References]

[1] Uchida R, et al. Andrastins A-C, new protein farnesyltransferase inhibitors produced by Penicillium sp. FO-3929. II. Structure elucidation and biosynthesis. J Antibiot (Tokyo). 1996 May;49(5):418-24. DOI:10.7164/antibiotics.49.418
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