| Identification | Back Directory | [Name]
ethyl rosmarinate | [CAS]
174591-47-0 | [Synonyms]
ethyl rosmarinate
Benzenepropanoic acid, α-[[(2E)-3-(3,4-dihydroxyphenyl)-1-oxo-2-propen-1-yl]oxy]-3,4-dihydroxy-, ethyl ester, (αR)- | [Molecular Formula]
C20H20O8 | [MDL Number]
MFCD32174350 | [MOL File]
174591-47-0.mol | [Molecular Weight]
388.37 |
| Chemical Properties | Back Directory | [Boiling point ]
658.7±55.0 °C(Predicted) | [density ]
1.413±0.06 g/cm3(Predicted) | [storage temp. ]
-20°C | [solubility ]
DMSO: 2mg/mL, clear | [form ]
Solid | [pka]
9.30±0.10(Predicted) | [color ]
White to off-white |
| Hazard Information | Back Directory | [Uses]
Ethyl rosmarinate is a phenolic compound that can be isolated from Lycopus lucidus. Ethyl rosmarinate has antioxidative activity. Ethyl rosmarinate inhibits lung inflammation[1][2]. | [Biological Activity]
Ethyl rosmarinate is an anti-inflammatory and antioxidative compound present in Lycopus lucidusHyptis suaveolens and other medical plants th at potently inhibits LPS induced production of nitric oxide and prostaglandin E2 in alveolar macrophages. Ethyl rosmarinate induces relaxation in aortic rings via an endothelium-independent pathway. | [References]
[1] Woo ER, et al. Antioxidative constituents from Lycopus lucidus. Arch Pharm Res. 2004 Feb;27(2):173-6. DOI:10.1007/BF02980102
[2] Thammason H, et al. Ethyl rosmarinate inhibits lipopolysaccharide-induced nitric oxide and prostaglandin E2 production in alveolar macrophages. Eur J Pharmacol. 2018 Apr 5;824:17-23. DOI:10.1016/j.ejphar.2018.01.042 |
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