| Identification | Back Directory | [Name]
Benzeneethanol, beta-amino-4-fluoro-, (betaR)- (9CI) | [CAS]
174770-74-2 | [Synonyms]
(R)-b-AMino-4-fluoro-benzeneethanol
(R)-2-AMino-2-(4-fluorophenyl)ethanol
(2R)-2-amino-2-(4-fluorophenyl)ethanol
(R)-2-Amino-2-(4-fluorophenyl)ethan-1-ol
Benzeneethanol, β-amino-4-fluoro-, (βR)-
(R)-2-AMINO-2-(4-FLUOROPHENYL)ETHANOL HCL
(2R)-2-AMINO-2-(4-FLUOROPHENYL)ETHAN-1-OL
Benzeneethanol, beta-aMino-4-fluoro-, (betaR)-
Benzeneethanol, beta-amino-4-fluoro-, (betaR)- (9CI) | [Molecular Formula]
C8H10FNO | [MDL Number]
MFCD09253715 | [MOL File]
174770-74-2.mol | [Molecular Weight]
155.17 |
| Chemical Properties | Back Directory | [Boiling point ]
287.4±25.0 °C(Predicted) | [density ]
1.208±0.06 g/cm3(Predicted) | [storage temp. ]
Keep in dark place,Sealed in dry,2-8°C | [pka]
12.48±0.10(Predicted) | [Appearance]
Off-white to light yellow Solid | [Optical Rotation]
Consistent with structure | [InChI]
InChI=1/C8H10FNO/c9-7-3-1-6(2-4-7)8(10)5-11/h1-4,8,11H,5,10H2/t8-/s3 | [InChIKey]
SRQPEYLZIUEVIA-SBYBRXNCNA-N | [SMILES]
C1([C@@H](N)CO)=CC=C(F)C=C1 |&1:1,r| |
| Hazard Information | Back Directory | [Chemical Properties]
(R)-2-Amino-2-(4-fluorophenyl)ethanol is a white solid. | [Uses]
(R)-2-Amino-2-(4-fluorophenyl)ethanol is used for synthesis of organic compounds. | [Hazard]
H302: Harmful if swallowed.
H315: Causes skin irritation.
H319: Causes serious eye irritation.
H335: May cause respiratory irritation. | [Synthesis]
To a stirred solution of lithium aluminium hydride (1.0 M in THF, 11.9 ml, 11.9 mmol) at 0℃ was added 4- (R)-fluorophenylglycine (1.0 g, 5.9 mmol) portion wise over 1 hour. The mixture was stirred at room temperature for 16 hours. Water (0.45 ml), 4 NNaOH (0.45 ml) and water (1.34 ml) was added to the mixture and the mixture was stirred for 10 minutes before being filtered. The filtrate was concentrated to give a yellow residue, (R)-2-Amino-2-(4-fluorophenyl)ethanol. | [References]
[1] Patent: US5952369, 1999, A
[2] Patent: US5998440, 1999, A
[3] Patent: US5854268, 1998, A |
|
| Company Name: |
NovoChemy Ltd.
|
| Tel: |
86-(0)21-31261262 373522135 |
| Website: |
www.novochemy.com |
| Company Name: |
Wuxi AppTec
|
| Tel: |
022-59987777 13552403979 |
| Website: |
www.labnetwork.com |
| Company Name: |
Mirro Chemical Co.,Ltd.
|
| Tel: |
0086-15313090952 |
| Website: |
www.chemicalbook.com/ShowSupplierProductsList30258/0_EN.htm |
|