ChemicalBook--->CAS DataBase List--->17688-29-8

17688-29-8

17688-29-8 Structure

17688-29-8 Structure
IdentificationBack Directory
[Name]

L-a-Lecithin-diarachidonoyl
[CAS]

17688-29-8
[Synonyms]

20:4 (Cis) PC
L-a-DiarachidonoylLecithin
L-a-Lecithin-diarachidonoyl
1,2-Diarachidonoyl-sn-glycero-3-PC
β,γ-diarachidoyl-L-α-phosphatidylcholine
1,2-diarachidonoyl-glycero-3-phosphocholine
1,2-di-O-arachidonoyl-sn-glycero-3-phosphocholine
[Molecular Formula]

C48H80NO8P
[MDL Number]

MFCD00171670
[MOL File]

17688-29-8.mol
[Molecular Weight]

830.14
Chemical PropertiesBack Directory
[storage temp. ]

-20°C
[solubility ]

Ethanol: 25 mg/ml
[form ]

Liquid
[color ]

Colorless to light yellow
[InChIKey]

LZLVZIFMYXDKCN-HLKGGLNDSA-N
[SMILES]

[P](=O)([O-])(OC[C@H](OC(=O)CCC\C=C/C\C=C/C\C=C/C\C=C\CCCCC)COC(=O)CCC\C=C/C\C=C/C\C=C/C\C=C/CCCCC)OCC[N+](C)(C)C
Safety DataBack Directory
[Symbol(GHS) ]

Flame (GHS02)Exclamation Mark (GHS07)
GHS02,GHS07
[Signal word ]

Danger
[Hazard statements ]

H225-H319
[Precautionary statements ]

P210-P233-P240-P241-P242-P243-P264-P280-P303+P361+P353-P305+P351+P338-P337+P313-P370+P378-P403+P235-P501
[WGK Germany ]

WGK 3
[Storage Class]

6.1D - Non-combustible acute toxic Cat.3
toxic hazardous materials or hazardous materials causing chronic effects
[Hazard Classifications]

Acute Tox. 3 Inhalation
Acute Tox. 4 Oral
Carc. 2
Eye Irrit. 2
Repr. 2
Skin Irrit. 2
STOT RE 1 Oral
STOT SE 3
Hazard InformationBack Directory
[Description]

1,2-Diarachidonoyl-sn-glycero-3-PC is a phospholipid containing the polyunsaturated long-chain (20:4) arachidonic acid inserted at the sn-1 and sn-2 positions. It can be used in the generation of micelles, liposomes, and other types of artificial membranes.
[Uses]

L-?a-?Lecithin-?diarachidonoyl is used in the preparation of compounds and lipid nanoparticle compounds for intracellular delivery of therapeutic agents.
[Definition]

ChEBI: A 1,2-diacyl-sn-glycero-3-phosphocholine in which the phosphatidyl acyl groups at positions 1 and 2 are both arachidonoyl.
[References]

[1] SCHWIEGER C, ACHILLES A, SCHOLZ S, et al. Binding of amphiphilic and triphilic block copolymers to lipid model membranes: the role of perfluorinated moieties[J]. Soft Matter, 2014, 33: 6147-6160. DOI: 10.1039/c4sm00830h
[2] MATHEUS MALTA DE Sá. Understanding Miltefosine–Membrane Interactions Using Molecular Dynamics Simulations[J]. Langmuir, 2015, 31 15: 4503-4512. DOI: 10.1021/acs.langmuir.5b00178
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