| Identification | Back Directory | [Name]
2-Propenoic acid, 3-(3,4,5-trihydroxyphenyl)-, decyl ester, (2E)- | [CAS]
1770778-45-4 | [Synonyms]
2-Propenoic acid, 3-(3,4,5-trihydroxyphenyl)-, decyl ester, (2E)- | [Molecular Formula]
C19H28O5 | [MDL Number]
MFCD34167522 | [MOL File]
1770778-45-4.mol | [Molecular Weight]
336.42 |
| Chemical Properties | Back Directory | [Boiling point ]
514.2±50.0 °C(Predicted) | [density ]
1.143±0.06 g/cm3(Predicted) | [storage temp. ]
Store at -20°C | [solubility ]
DMSO: 100 mg/mL (297.25 mM) | [form ]
Solid | [pka]
8.82±0.15(Predicted) | [color ]
White to off-white |
| Hazard Information | Back Directory | [Uses]
3,4,5-Trihydroxycinnamic acid decyl ester is an excellent inhibitor of lipid absorption and accumulation, with anti-obesity properties. 3,4,5-Trihydroxycinnamic acid decyl ester is a pancreatic lipase inhibitor, with an EC50 of approximately 0.9 μM[1]. | [in vivo]
3,4,5-Trihydroxycinnamic acid decyl ester (30-150 mg/kg; p.o.) suppresses a rise in blood triglyceride (TG) levels in mice given corn oil orally[1].
| Animal Model: | 6 weeks old Male ddY mice[1] | | Dosage: | 30 mg/kg, 150 mg/kg | | Administration: | Oral administration | | Result: | Reduced plasma TG in a dose-dependent manner. |
| [References]
[1] Masahiko Imai ,et al. Inhibitory effects of hydroxylated cinnamoyl esters on lipid absorption and accumulation. Bioorg Med Chem. 2015 Jul 1;23(13):3788-95. DOI:10.1016/j.bmc.2015.03.086 |
|
| Company Name: |
MedChemExpress
|
| Tel: |
021-58955995 |
| Website: |
www.medchemexpress.com |
|