| Identification | Back Directory | [Name]
4-amino-7-iodopyrrolo[2,1-f][1,2,4]triazine | [CAS]
1770840-43-1 | [Synonyms]
SKL530
Remdesivir-004
Starting material)
4-Amino-7-iodopyrroL
Remdesivir Impurity 20
o[2,1-f][1,2,4]triazine
7-iodopyrrolo[2,1-f][1,2,4]triazin-4-
7-iodopyrrole[2,1-f][1,2,4]triazin-4-amine
4-amino-7-iodopyrrolo[2,1-f][1,2,4]triazine
Pyrrolo[2,1-f][1,2,4]triazin-4-amine, 7-iodo-
7-iodopyrrole [1, 2-F][1,2,4] triazine-4-amine
7-iodopyrrolido [2,1-F][1,2,4] triazine -4 - amine
GS-441524，7-iodopyrrolo[2,1-f][1,2,4]triazin-4- amine | [EINECS(EC#)]
204-514-8 | [Molecular Formula]
C6H5IN4 | [MDL Number]
MFCD21607515 | [MOL File]
1770840-43-1.mol | [Molecular Weight]
260.04 |
| Chemical Properties | Back Directory | [density ]
2.43±0.1 g/cm3(Predicted) | [form ]
solid | [pka]
3.04±0.30(Predicted) | [color ]
Pale yellow | [InChI]
InChI=1S/C6H5IN4/c7-5-2-1-4-6(8)9-3-10-11(4)5/h1-3H,(H2,8,9,10) | [InChIKey]
ZEBGLCLVPCOXIV-UHFFFAOYSA-N | [SMILES]
N12C(I)=CC=C1C(N)=NC=N2 |
| Hazard Information | Back Directory | [Uses]
4-amino-7-iodopyrrolo[2,1-f][1,2,4]triazine is an amine organic substance and can be used as an intermediate for APIs. | [Synthesis]
The synthesis reaction of 4-amino-7-iodopyrrolo [2,1-f ] [1,2,4] triazine is as follows:
4-amino pyrrolo [2,1-f ] [1,2,4] triazine reacts with iodine or iodine chloride under mild conditions to generate most of iodinated products, isomers and diiodized products are not generated under the mild conditions, and unreacted materials react with N-iodosuccinimide to further ensure that raw materials completely react, so that the conversion rate of the raw materials is improved, and the generation of the isomer products and the diiodized products is also inhibited.
![Synthesis of 7-Iodopyrrolo[2,1-f][1,2,4]triazin-4-amine](/NewsImg/2026-01-13/6390389731793011412642177.png "Synthesis of 7-Iodopyrrolo[2,1-f][1,2,4]triazin-4-amine") |
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