| Identification | Back Directory | [Name]
4-Pyridinecarboxamide, 2-[(cyclopropylcarbonyl)amino]-N-[4-(4-fluorophenyl)-3-pyridinyl]- | [CAS]
1772823-37-6 | [Synonyms]
4-Pyridinecarboxamide, 2-[(cyclopropylcarbonyl)amino]-N-[4-(4-fluorophenyl)-3-pyridinyl]- | [Molecular Formula]
C21H17FN4O2 | [MOL File]
1772823-37-6.mol | [Molecular Weight]
376.38 |
| Chemical Properties | Back Directory | [Boiling point ]
565.3±50.0 °C(predicted) | [density ]
1.411±0.06 g/cm3(Temp: 20 °C; Press: 760 Torr)(predicted) | [pka]
11.47±0.70(predicted) |
| Hazard Information | Back Directory | [Uses]
GSK-3 inhibitor 6 (2) is a CNS penetrated GSK-3 inhibitor, with IC50 values of 29 nM and 24 nM for GSK-3α and GSK-3β, respectively[1]. | [References]
[1] Surendra Reddy Gundam, et al. Synthesis and preliminary evaluation of novel PET probes for GSK-3 imaging. Sci Rep. 2024 Jul 10;14(1):15960. DOI:10.1038/s41598-024-65943-z |
|
|