| Identification | Back Directory | [Name]
Methanone, 3-furanyl[4-[2-(2-methoxyphenyl)-5-phenylpyrazolo[1,5-a]pyrimidin-7-yl]-1-piperazinyl]- | [CAS]
1776055-29-8 | [Synonyms]
Efflux inhibitor-1
Methanone, 3-furanyl[4-[2-(2-methoxyphenyl)-5-phenylpyrazolo[1,5-a]pyrimidin-7-yl]-1-piperazinyl]- | [Molecular Formula]
C28H25N5O3 | [MOL File]
1776055-29-8.mol | [Molecular Weight]
479.53 |
| Hazard Information | Back Directory | [Uses]
Efflux inhibitor-1 (compound 2) is a pyrazolo[1,5-a]pyrimidine efflux inhibitor. Efflux inhibitor-1 selectively targets toward ABCG2/BCRP over ABCB1 with IC50s of 0.45 μM and 2.17 μM, respectively[1]. | [References]
[1] Larson, et al. Selective efflux inhibitors and related pharmaceutical compositions and methods of treatment: United States, US9056111[P]. 2015-06-16. |
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