ChemicalBook--->CAS DataBase List--->177748-20-8

177748-20-8

177748-20-8 Structure

177748-20-8 Structure
IdentificationBack Directory
[Name]

4-Pivaloyloxy Toremifene
[CAS]

177748-20-8
[Synonyms]

Toremifene Impurity 11
4-Pivaloyloxy Toremifene
QKWCTPTUWXTFRE-ZQHSETAFSA-N
Propanoic acid, 2,2-dimethyl-, 4-[(1E)-4-chloro-1-[4-[2-(dimethylamino)ethoxy]phenyl]-2-phenyl-1-buten-1-yl]phenyl ester
[Molecular Formula]

C31H36ClNO3
[MOL File]

177748-20-8.mol
[Molecular Weight]

506.08
Chemical PropertiesBack Directory
[Melting point ]

124-127°C
[Boiling point ]

611.2±55.0 °C(Predicted)
[density ]

1.112±0.06 g/cm3(Predicted)
[storage temp. ]

Amber Vial, -20°C Freezer, Under inert atmosphere
[solubility ]

Chloroform, Methanol
[form ]

Oil
[pka]

8.68±0.28(Predicted)
[color ]

Yellow
Hazard InformationBack Directory
[Chemical Properties]

Pale Yellow Oil
[Uses]

Protected 4’Hydroxy Toremifene (H954510), a metabolite of Toremifene
[Uses]

Protected 4-Hydroxy Toremifene (H954500), a metabolite of Toremifene (T547500). 4-Pivaloyloxy Toremifene is used in the preparation of Tamoxifen (T006000) analogs with improved binding selectivity towards the orphan estrogen-related receptor γ and the classical estrogen receptor α.
[Uses]

Protected 4-Hydroxy Toremifene (H954500), a metabolite of Toremifene wards the orphan estrogen-related receptor γ and the classical estrogen receptor α.
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