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1778219-81-0

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1778219-81-0 Structure

1778219-81-0 Structure
IdentificationBack Directory
[Name]

m-PEG3-t-butyl ester
[CAS]

1778219-81-0
[Synonyms]

m-PEG3-Boc
m-PEG3-t-butyl ester
tert-butyl 3-(2-(2-methoxyethoxy)ethoxy)propanoate
[Molecular Formula]

C12H24O5
[MDL Number]

MFCD29764320
[MOL File]

1778219-81-0.mol
[Molecular Weight]

248.32
Chemical PropertiesBack Directory
[Boiling point ]

302.8±22.0 °C(Predicted)
[density ]

0.996±0.06 g/cm3(Predicted)
Hazard InformationBack Directory
[Description]

m-PEG3-t-butyl ester is a PEG linker containing a t-butyl ester. The t-butyl protected carboxyl group can be deprotected under acidic conditions. The hydrophilic PEG spacer increases solubility in aqueous media.
[Uses]

m-PEG3-Boc is a PEG- and Alkyl/ether-based PROTAC linker can be used in the synthesis of PROTACs[1].
[IC 50]

Alkyl/ether; PEGs
[References]

[1] Darren H. Wakefield, et al. Poly(vinyl ester) Polymers for In Vivo Nucleic Acid Delivery. US20130121954A1.
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