| Identification | Back Directory | [Name]
Hel 13 - 5 | [CAS]
177942-21-1 | [Synonyms]
Hel 13 - 5
L-Leucine, L-lysyl-L-leucyl-L-leucyl-L-lysyl-L-leucyl-L-leucyl-L-leucyl-L-lysyl-L-leucyl-L-tryptophyl-L-leucyl-L-lysyl-L-leucyl-L-leucyl-L-lysyl-L-leucyl-L-leucyl- | [Molecular Formula]
C113H204N24O19 | [MOL File]
177942-21-1.mol | [Molecular Weight]
2202.98 |
| Chemical Properties | Back Directory | [Boiling point ]
1967.1±65.0 °C(Predicted) | [density ]
1.121±0.06 g/cm3(Predicted) | [pka]
3.41±0.10(Predicted) | [Sequence]
Lys-Leu-Leu-Lys-Leu-Leu-Leu-Lys-Leu-Trp-Leu-Lys-Leu-Leu-Lys-Leu-Leu-Leu |
| Hazard Information | Back Directory | [Uses]
Hel 13-5 is a monomeric synthetic peptide based on the N-terminal segment of human SP-B. Hel 13-5 mainly is a-helical and consists of 13 hydrophobic and 5 hydrophilic amino acid residues. Hel 13-5 can be used in combination with phospholipids for developing pulmonary surfactant model systems[1][2]. | [References]
[1] Nakahara H, et al. Pulmonary surfactant model systems catch the specific interaction of an amphiphilic peptide with anionic phospholipid. Biophys J. 2009 Feb 18;96(4):1415-29. DOI:10.1016/j.bpj.2008.11.022
[2] Nakahara H, et al. Langmuir monolayer of artificial pulmonary surfactant mixtures with an amphiphilic peptide at the air/water interface: comparison of new preparations with surfacten (Surfactant TA). Langmuir. 2008 Apr 1;24(7):3370-9. DOI:10.1021/la703180x |
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