| Identification | Back Directory | [Name]
2(3H)-Benzoxazolone, 6-[3-[4-[(4-fluorophenyl)methyl]-1-piperidinyl]-1-oxopropyl]- | [CAS]
178165-43-0 | [Synonyms]
2(3H)-Benzoxazolone, 6-[3-[4-[(4-fluorophenyl)methyl]-1-piperidinyl]-1-oxopropyl]- | [Molecular Formula]
C22H23FN2O3 | [MOL File]
178165-43-0.mol | [Molecular Weight]
382.43 |
| Hazard Information | Back Directory | [Uses]
EMD-95885 is a selective NR2B-containing NMDA receptors antagonist with an IC50 of 3.9 nM. EMD-95885 does not interact with other sites on the NMDA receptor[1]. | [IC 50]
NR2B: 3.9 nM (IC50) | [References]
[1] Roger G, et al. Radiosynthesis and pharmacological evaluation of [11C]EMD-95885: a high affinity ligand for NR2B-containing NMDA receptors. Bioorg Med Chem. 2004 Jun 15;12(12):3229-37. DOI:10.1016/j.bmc.2004.03.065 |
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