ChemicalBook--->CAS DataBase List--->1783-84-2

1783-84-2

1783-84-2 Structure

1783-84-2 Structure
IdentificationBack Directory
[Name]

CIS-8,11,14-EICOSATRIENOIC ACID
[CAS]

1783-84-2
[Synonyms]

DGLA
20:3(n-6)
Ro 12-1989
Diroleuton
Murepavadin
(8Z,11Z,14Z)
homo-γ-linolenic acid
w6-Eicosatrienoic acid
BishoMo-γ-linolenic Acid
DIHOMO-GAMMA-LINOLEICACID
HOMO-GAMMA-LINOLENIC ACID
DIHOMO-GAMMA-LINOLENIC ACID
-Icosa-8,11,14-trienoic acid
8Z,11Z,14Z-EICOSATRIENOIC ACID
EICOSA-8Z,11Z,14Z-TRIENOIC ACID
CIS-8,11,14-EICOSATRIENOIC ACID
cis-8,11,14-Dicosatrienoic acid
Homo-Gamma-Linolenic Acid(C20:3)
all cis-8,11,14-Icosatrienoic Acid
Methyl cis-8,11,14-eicosatrienoate
(Z,Z,Z)-icosatri-8,11,14-enoic acid
(Z,Z,Z)-8,11,14-Eicosatrienoic Acid
8,11,14-all-cis-Eicosatrienoic acid
all-cis-8,11,14-Eicosatrienoic Acid
all-cis-icosa-8,11,14-trienoic acid
Dihomo-γ-linolenic Acid (20:3, n-6)
all cis-8,11,14-Eicosatrienoic Acid >
cis-8,cis-11,cis-14-Eicosatrienoic Acid
8-cis,11-cis,14-cis-Eicosatrienoic acid
(9Z,12Z,15Z)-9,12,15-Icosatrienoic acid
(8Z,11Z,14Z)-8,11,14-Icosatrienoic acid
CIS,CIS,CIS-8,11,14-EICOSATRIENOIC ACID
(8Z,11Z,14Z)-Icosa-8,11,14-trienoic acid
(8Z,11Z,14Z)-8,11,14-Eicosatrienoic Acid
(8Z,11E,14E)-icosa-8,11,14-trienoic acid
(6Z,9Z,12Z)-octadeca-6,9,12-trienoic acid
8,11,14-Eicosatrienoic acid, (8Z,11Z,14Z)-
DELTA 8 CIS 11 CIS 14 CIS EICOSATRIENOIC ACID
DIHOMO-GAMMA-LINOLENIC ACID-CONTAINING TRIGLYCERIDE
cis-8,11,14-Eicosatrienoic acid Methyl ester (C20:3n6)
cis-8,11,14-Eicosatrienoic acid Methyl ester (C20:3n6) Solution
[EINECS(EC#)]

217-233-0
[Molecular Formula]

C20H34O2
[MDL Number]

MFCD00065721
[MOL File]

1783-84-2.mol
[Molecular Weight]

306.48
Chemical PropertiesBack Directory
[Boiling point ]

200°C(lit.)
[density ]

0.917±0.06 g/cm3(Predicted)
[refractive index ]

n20/D 1.478(lit.)
[Fp ]

144 °F
[storage temp. ]

−20°C
[solubility ]

chloroform: 50 mg/mL, clear, colorless
[form ]

Liquid
[pka]

4.77±0.10(Predicted)
[color ]

Colourless to Light Yellow
[biological source]

plant oil (Borage)
[BRN ]

1796533
[Stability:]

Light Sensitive
[Cosmetics Ingredients Functions]

SKIN CONDITIONING
[InChI]

1S/C20H34O2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20(21)22/h6-7,9-10,12-13H,2-5,8,11,14-19H2,1H3,(H,21,22)/b7-6-,10-9-,13-12-
[InChIKey]

HOBAELRKJCKHQD-QNEBEIHSSA-N
[SMILES]

CCCCC\C=C/C\C=C/C\C=C/CCCCCCC(O)=O
Safety DataBack Directory
[Symbol(GHS) ]

Exclamation Mark (GHS07)
GHS07
[Signal word ]

Warning
[Hazard statements ]

H227
[Precautionary statements ]

P210-P280-P403+P235-P501
[Safety Statements ]

23-24/25
[RIDADR ]

NA 1993 / PGIII
[WGK Germany ]

3
[RTECS ]

JX3880000
[F ]

8-10-23
[HS Code ]

2916.19.3000
[Storage Class]

10 - Combustible liquids
Hazard InformationBack Directory
[Description]

Dihomo-γ-linolenic acid (DGLA) is a 20-carbon ω?6 fatty acid. In physiological literature, it is given the name 20:3 (ω?6). DGLA is a carboxylic acid with a 20-carbon chain and three cis double bonds; the first double bond is located at the sixth carbon from the omega end. DGLA is the elongation product of γ-linolenic acid (GLA; 18:3, ω?6). GLA, in turn, is a desaturation product of linoleic acid (18:2, ω?6). DGLA is made in the body by the elongation of GLA, by an efficient enzyme which does not appear to suffer any form of (dietary) inhibition. DGLA is an extremely uncommon fatty acid, found only in trace amounts in animal products.
[Chemical Properties]

Clear Colourless Oil
[Uses]

cis-8,11,14-Eicosatrienoic acid is a fatty acid which has selective tumoricidal action.
[Definition]

ChEBI: An icosatrienoic acid having three cis double bonds at positions 8, 11 and 14.
[General Description]

cis-8,11,14-Eicosatrienoic acid is an unsaturated fatty acid, present in various plant species including Echium Rauwolfii, Sisymbrium Irio, Rhytididelphus squarrosus (Hedw.) Warnst etc, which are of pharmaceutical interest.
[Biological Activity]

Beneficial effects in cardiovascular diseases and inflammation.
Spectrum DetailBack Directory
[Spectrum Detail]

CIS-8,11,14-EICOSATRIENOIC ACID(1783-84-2)1HNMR
CIS-8,11,14-EICOSATRIENOIC ACID(1783-84-2)IR
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