| Identification | Back Directory | [Name]
3-(3-Fluorophenyl)-5,5-diMethyl-4-[4-(Methylsulfonyl)phenyl]-2(5H)-furanone | [CAS]
178402-36-3 | [Synonyms]
DFU
CID 9906892
3-(3-fluorophenyl)-5,5-dimethyl-4-(4-methylsulfonylphenyl)furan-2-one
3-(3-Fluorophenyl)-5,5-diMethyl-4-[4-(Methylsulfonyl)phenyl]-2(5H)-furanone
5,5-Dimethyl-3-(3 fluorophenyl)-4-(4 methylsulphonal) phenyl-2 (5H)-furanone
2(5H)-Furanone, 3-(3-fluorophenyl)-5,5-dimethyl-4-[4-(methylsulfonyl)phenyl]- | [Molecular Formula]
C19H17FO4S | [MDL Number]
MFCD00949692 | [MOL File]
178402-36-3.mol | [Molecular Weight]
360.4 |
| Chemical Properties | Back Directory | [Boiling point ]
567.9±50.0 °C(Predicted) | [density ]
1.294±0.06 g/cm3(Predicted) | [storage temp. ]
2-8°C | [solubility ]
DMSO: soluble10mg/mL, clear | [form ]
powder | [color ]
white to beige |
| Hazard Information | Back Directory | [Uses]
3-(3-Fluorophenyl)-5,5-dimethyl-4-[4-(methylsulfonyl)phenyl]-2(5H)-furanone is a potential cyclooxygenase-1 inhibitor used to treat vascular disease. | [Biological Activity]
DFU is an orally available highly selective cyclo-oxygenase-2 (COX-2) inhibitor th at potently inhibits lipopolysaccharide (LPS)-induced PGE2 production in a human whole blood assay. |
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| Company Name: |
Energy Chemical
|
| Tel: |
021-58432009 400-005-6266 |
| Website: |
http://www.energy-chemical.com |
| Company Name: |
Merck KGaA
|
| Tel: |
21-20338288 |
| Website: |
www.sigmaaldrich.cn |
|