| Identification | Back Directory | [Name]
APC 366 | [CAS]
178925-65-0 | [Synonyms]
APC 366
APC-366 HCl
N-(1-Hydroxy-2-naphthoyl)-L-arginyl-L-prolinamide
N-(1-Hydroxy-2-naphthoyl)-L-arginine-L-prolinamide | [Molecular Formula]
C22H28N6O4 | [MDL Number]
MFCD00934212 | [MOL File]
178925-65-0.mol | [Molecular Weight]
476.96 |
| Hazard Information | Back Directory | [Uses]
APC 366 is a mast tryptase inhibitor, which prevents hepatic fibrosis by inhibiting collagen synthesis induced by tryptase/protease-activated receptor 2 interactions in hepatic stellate cells. | [Biological Activity]
Selective inhibitor of mast cell tryptase (K i = 7.1 μ M) that inhibits tryptase-induced histamine release from human tonsil and lung cells. Reduces airway inflammation and blocks postchallenge airway hyperresponsiveness in vivo . |
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| Company Name: |
BOC Sciences
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| Tel: |
1-631-485-4226; 16314854226 |
| Website: |
https://www.bocsci.com |
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