| Identification | Back Directory | [Name]
(2R,3S,5R)-5-(4-Chloro-5-iodo-7H-pyrrolo[2,3-d]pyrimidin-7-yl)-2-(hydroxymethyl)tetrahydrofuran-3-ol | [CAS]
178995-71-6 | [Synonyms]
4-Chloro-5-iodo-7-(2-deoxy--D-ribofuranosyl)-7H-pyrrolo[2,3-d]pyrimidine
4-Chloro-5-iodo-7-(2-deoxy-b-D-ribofuranosyl)-7H-pyrrolo[2,3-d]pyrimidine
4-Chloro-5-iodo-7-(2-deoxy-beta-D-ribofuranosyl)-7H-pyrrolo[2,3-d]pyrimidine
4-Chloro-7-(2-deoxy-α-D-erythro-pentofuranosyl)-5-iodo-7H-pyrrolo[2,3-d]pyrimidine
7H-Pyrrolo[2,3-d]pyrimidine, 4-chloro-7-(2-deoxy-β-D-erythro-pentofuranosyl)-5-iodo-
(2R,3S,5R)-5-(4-chloro-5-iodopyrrolo[2,3-d]pyrimidin-7-yl)-2-(hydroxymethyl)oxolan-3-ol
(2R,3S,5R)-5-(4-Chloro-5-iodo-7H-pyrrolo[2,3-d]pyrimidin-7-yl)-2-(hydroxymethyl)tetrahydrofuran-3-ol | [Molecular Formula]
C11H11ClIN3O3 | [MDL Number]
MFCD28368490 | [MOL File]
178995-71-6.mol | [Molecular Weight]
395.58 |
| Hazard Information | Back Directory | [Uses]
4-Chloro-7-(2-deoxy-β-D-erythro-pentofuranosyl)-5-iodo-7H-pyrrolo[2,3-d]pyrimidine is a pyrimidine nucleoside analog. Pyrimidine nucleoside analogs have a wide range of biochemical and anticancer activities. These include DNA synthesis inhibition, RNA synthesis inhibition, antiviral effects, and immunomodulatory effects[1]. | [References]
[1] Galmarini CM, et al. Pyrimidine nucleoside analogs in cancer treatment. Expert Rev Anticancer Ther. 2003 Oct;3(5):717-28. DOI:10.1586/14737140.3.5.717 |
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