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1799421-66-1

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1799421-66-1 Structure

1799421-66-1 Structure

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[Name] N3-L-Cit-OH*DCHA
[CAS] 1799421-66-1
[Synonyms] N3-L-Cit-OH N3-L-Cit-OH*DCHA
[Molecular Formula] C6H11N5O3
[MOL File] 1799421-66-1.mol
[Molecular Weight] 201.19

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[Uses] N3-L-Cit-OH is a click chemistry reagent containing an azide group. N3-L-Cit-OH can be used to construct peptidomimetic ADC linkers using Click-chemistry[1]. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.
[References] [1] Eigenbrot C, et al. Discovery of Peptidomimetic Antibody-Drug Conjugate Linkers with Enhanced Protease Specificity. J Med Chem. 2018 Feb 8;61(3):989-1000. DOI:10.1021/acs.jmedchem.7b01430

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Company Name:	Alfa Chemistry
Tel:	+1-5166625404;
Website:	https://www.alfa-chemistry.com/

Company Name:	TargetMol Chemicals Inc.
Tel:	15002134094
Website:	https://www.targetmol.cn/

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