| Identification | Back Directory | [Name]
1H-Benzimidazole-7-carboxylic acid, 2-[4'-[[3-(acetylamino)phenyl]methoxy][1,1'-biphenyl]-4-yl]-5-methyl- | [CAS]
1799734-10-3 | [Synonyms]
1H-Benzimidazole-7-carboxylic acid, 2-[4'-[[3-(acetylamino)phenyl]methoxy][1,1'-biphenyl]-4-yl]-5-methyl- | [Molecular Formula]
C30H25N3O4 | [MOL File]
1799734-10-3.mol | [Molecular Weight]
491.54 |
| Hazard Information | Back Directory | [Uses]
UM-C162, a benzimidazole derivative, can rescue nematodes from a S. aureus infection. UM-C162 prevents the formation of biofilm without interfering with bacterial viability. UM-C162 mediates the disruption of S. aureus hemolysins, proteases and clumping factors production. UM-C162 has the potential to be used as an anti-virulence agent to control S. aureus infections[1]. | [References]
[1] Cin Kong, et al. Suppression of Staphylococcus aureus biofilm formation and virulence by a benzimidazole derivative, UM-C162. Sci Rep. 2018 Feb 9;8(1):2758. DOI:10.1038/s41598-018-21141-2 |
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